Magyar Nőorvosok Lapja
Keresés eredménye
Fetal growth and insulin-like growth factor system
Insulin-like growth factors (IGF-I and IGF-II) stimulate extravillous trophoblast (EVT) cells migration and invasion into uterine wall and one of IGF binding proteins (IGFBPs), IGFBP-1 inhibits IGF action thereby regulating EVT cells invasion negatively. Thus, appropriate placentation is determined by the balance of IGF and IGFBP-1 in maternal-fetal interface. IGF-I stimulates amino acids uptake by trophoblast cells in vitro and enhances the ...